We all know that genes are responsible for the making,
regulation and manipulation of an organism. Genes as represented by series of
DNA or RNA are considered to have recorded and passed the influence of the
environment to the next generation via mutation. It is not necessarily mutation
that passes the gene manipulation to the next generation. Organisms can change
their DNA according to the conditions that they are presented with. It is not a
self controlled process but yet the gene pool of an organism could be altered
without mutations.
The DNA of an organism is the blue print of its building up.
As the embryo grows up, the new organism is formed. The DNA is mixed from paternal
and maternal reproductive cells. It is not necessary to have fusion of male and
female reproductive cells in order to mix the DNA. The process could also take
place in ordinary cells.
There must be other cells that mix their DNA in the process
of cell division and cell growth. The most probable candidates for DNA mix up
could be the ones that are exposed to the environment. The cells of the
epidermis of any organism or the cells that are in touch with the environment
should show DNA mixing and splitting as they divide into many cells.
The change in the DNA in cells other than the gametocytes
would not influence the current structure of the organism. The purpose or the
product of the change in the DNA of other cells should be to pass the recorded
information to the next generation of cells.
The gametocytes should represent the changes in somatic cell
DNA in some way. The more similar changes take place in somatic cells would be
represented in the making of the gametes.
I am not telling fairy tales, it is just that I don’t have
the facilities to conduct experiments and prove my theories. So I propose the
experiments for anyone to conduct and disprove before being skeptical.
Experiment:
A small multi cellular organism has to be selected for the
experiment where the number of cells in that organism should be in the order of
thousands. It will be easier to manipulate higher ratios of cells in the
organisms in order to observe the results in the next generation.
Take only one male and one female organism but in two separate
vessels. Insert any gene that could be recognized by its product; like the gene
responsible for secreting insulin. The same technology that is used to
commercially produce insulin through bacterial colonies could be used. The gene
does not have to be inserted into the DNA of the somatic cells in the organism.
Just introducing maximum quantity of genes into the medium should be enough for
the genes to be taken into the organisms. The male and female organism will
intake the genes but not into their DNAs. The introduced gene just has to be inside
the somatic cells. The more number of cells intake the gene, the more the germ
cells would respond to the presence of a foreign gene.
Once the genes have been taken into the organisms, the
organisms should be transferred to fresh medium and into one vessel so that
they can start reproducing. Now the medium will not have insulin genes but the
somatic cells of the organisms will. In the resulting organisms ( the next
generation ) there will be cells with insulin genes incorporated into their own
DNA or genes related to the insulin genes (derivatives or deviations of the
insulin gene).
A fine tuned experiment would be to insert the foreign genes
into the somatic cells and not into the germ cells. This would be time
consuming and extremely difficult as inserting DNA fragments separately into
the somatic cells of a living organism might kill the organism; but if it could
be performed, then the result would be fined tuned too.
Experiment 2:
Grafting of plants is another way to see the gene mixing in
somatic cells. If you graft two species of plants that belong to the same genre
or family, then you will have a zone where there are cells of both species
present. This area will actually not hold just two different sets of genes. The
cells in the transformation zone of the grafted area will hold thousand of
different cells with entirely different genes. The transformation zone will
have cells with the gene pools of the original two species and a number of
transformational gene pools between the two species. If you can extract the
cells at different parts of the grafted area and reproduce them into new plants
through tissue culture, then the resulting plants will have both the original
species and a number of new species formed. Some of them will be fertile and
most of them would not be. These somatic cells would have the information
recorded to affect the germ cells so that the germ cells would pass the
information about the changes in the organism and the environment to the next
generation of plants.
Also if you had two grafted plants and made them pollinate,
the seeds produced will have the information about the grafting. In the
siblings germinating from the seeds, there will be difference and correlation to
the original two species used in the experiments.
-End of Experiments-
The representation of the conditions of the organism and its
environment into the DNA of the somatic cells would have a probability. The representation
of the changes in the DNA of the somatic cells into the DNA of the gametes
would have another probability.
It is not fully conceivable to me to say which conditions
would alter the DNA of the somatic cells and which ones at the somatic cells
would be represented in the gametes. Important information will be carried out
to the next generation. Important information for the existence of an organism
or the continuation of a species is about the negative impacts more than
favorable ones.
Prominent and negative environmental conditions that are
experienced regularly by the organism would make changes in the DNA of the
somatic cells. I am not talking about the X ray and other mutation causing high
energy radiation.
I am talking about the less powerful but prominent conditions
such as slightly increased temperature, higher concentration of Carbon Dioxide
in the air or increased concentration of some particular micro nutrient in the
soil around the roots.
Experiment:
If you take a plant species that reproduces rapidly through
sexual reproduction and grow a colony of plants in ideal conditions for it,
they will reproduce and will give regular offspring. If you keep all other
conditions the same but increase the temperature of the environment by one
degree Celsius, then there will be changes in the somatic cells and the changes
will be represented in the gametes. The resulting offspring will have that
information.
If the plant population is left in an isolated environment
and left to reproduce generation after generation but exposed to the same
increased temperature, the latest generations will have information about the
environmental conditions and will start making adaptations to overcome the
barrier.
(if the plant species selected is very smaller, and the
reproductive duration is very smaller, then more generations will pass in
shorter time period and the results could be seen quickly)
-End of experiment-
So, evolution would take place faster in organisms that grow
up to reproductive age faster. And organism will evolve against difficult
conditions and not along favorable conditions. Not all parts of the DNA produce
amino acids or proteins. The majority of the DNA is junk (or at least is called
the junk DNA). There is no need to keep the junk in each and every single cell
in the organism. There is a cause and a purpose behind each and every single
nitrogen base in the DNA.
The coding DNA is the confirmed and necessary commands for
the making of the next generation of the organism and the blueprint of that
particular species. The non coding DNA is the information about the conditions
of the past organisms of the same species. It is the instruction manual for the
germ cells to produce gametes that would abide by the needs of the species. The
non coding DNA is the result of experience by the generations before the
current one. The non coding DNA is there as a reference to the history of the
species so that the germ cells would refer to their own non coding DNA and that
of the somatic cells and would see if there are any differences. Differences
that occurred similar to the ones occurred in the past could also be recognized
from the pattern of the non coding DNA. Any new types of differences in the non
coding DNA of the somatic cells would trigger adjustment of DNA in the gametes.
When chromosomes crossover to produce new combination of
genes, they take reference from the non coding DNA in order to confirm where to
split and where to join in meiosis.
Experiment:
Take a smaller and short living animal. Make a clone of that
particular animal and introduce a foreign gene into the DNA of the stem cell of
the clone. Insulin gene would be ideal. The cloned animal will have insulin
genes in all the cells including the germ cells.
Make the animal mate with an animal of the opposite sex. The
resulting offspring does not necessarily have to have insulin genes. Or the
gametes don’t even have to have the insulin genes as they form. That is because
the insulin genes are essentially part of coding DNA. This is not a reference
to some change inside the organism or outside it. It will not affect the non
coding DNA of the somatic cells. Hence, it will not be represented by the germ
cells as a reference to a change. But, the germ cells will notice that the gene
was not present in the past generations. This information is available in the
non coding DNA of the germ cells. So the germ cells will either eliminate this unnecessary
gene in the making of gametes or will make a note (produce a DNA series that
records this change) in the non coding DNA of the gametes.
-End of experiment-
Experiment 2
If you could cut off the entire non coding DNA and have only
the coding DNA of an organism, you could reproduce it asexually through mitosis.
But the germ cells of that organism will be unable to produce gametes as they
will miss the reference to make the gametes.
This could be performed in organisms that reproduce sexually
and asexually.
-End of Experiment-
The DNA is the most sensitive sensor in the universe. It can
sense each and every aspect of the entire environment. The making of the DNA is
so precise that it resembles a resonating string, an energy wave with a
particular wavelength and a regulated summation of information.
The design of the DNA makes it resonate and respond to
resonations, vibrations, sounds, light and all forms of energy and other
elements of the universe. A sound wave or an energy wave with the same wavelength
of the DNA (the length of a turn at every 34 Angstroms) will have direct impact
in the replication and manipulation of the DNA.
DNA is beyond the 3D wave form of sound and light. By the
way that the DNA coils itself and onto the histone proteins, the DNA is not
only a super coil, it also makes up a superwave that could align and conceive
waves of multiple wavelengths and of multiple dimensions.
Double helix DNA could be able to conceive dimensions that
are beyond consummation to equipments that man has made so far.
Experiment:
Take naked DNA in an appropriate vessel and expose it to 34
Angstrom wavelength of different sound and energy waves. The DNA will have direct
effects to the waves such as vibrating, coiling, stretching, resonating,
pulsing, capturing and releasing energy in sequences and or producing different
forms of energy and sound, vibration or resonance.
Waves with the amplitude of one, two or multiples of two nanometers
will have alignment of DNA double helix along the wave direction in addition to
the effects proposed above.
A perfect and regular wave with 34 Angstrom wavelength and amplitude
of one nanometer will have the DNA strand split as double helix and form a
single helix.
-End of Experiment-
There is much to the DNA than just biology. DNA is the tool
that the organisms have to conceive higher dimensions. As the body is filled
with multiple numbers of the same DNA sequences, the sensing through DNA is
like averaging trillions of readings for the same experiment to find the
accurate reading. The precision and accuracy of the sensing are beyond
comprehension and are not practical with any man made equipment.
If an energy wave passing through the human body is to be
sensed with the DNA of all cells, then the accuracy of the sensing will be many
numbers of times higher than advanced equipments used in advanced science laboratories
today.
The mechanism through which the changes in the non coding
DNA of the somatic cells are represented in the gametes is beyond my conception
for the moment. DNA is not some inactive sequence of molecules that are used as
a building guide for proteins. The DNA is very much active apart from its
biological responsibilities. The DNA is able to sense and produce magnetic,
electric and other fields. DNA can generate electricity. DNA can produce
resonance, vibration and all forms of energy. DNA could sense temporal and
spatial dimensions. DNA can format itself to be catalyst at different chemical
reactions. The DNA is like an artificially intelligent information system that
could perform on its own.
I will give a detailed explanation to the physical,
chemical, spatial and temporal capacities of the DNA in a separate post.
